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Welcome:
Welcome to the Jiang lab on systems immunology. A dysfunctional or dysregulated immune system not only fails to offer protection, it can also introduce unnecessary immune responses such as allergies or autoimmune diseases. The key to immune modulation and engineering and regenerative medicine is to understand how the normal immune system works. However, a full understanding of the complex interactions among immune cells and between immune cells and cytokines and chemokines requires a quantitative and systems approach. Using high-throughput sequencing and single-cell analysis in combination with quantitative analysis, we are interested in answering the following questions: How does the immune system develop and age? What are the molecular signatures of autoimmune diseases? Why does the immune system tolerate tumors? Answers to these questions are important in establishing metrics for immune health and providing biomarkers for diagnosis and therapy.
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News
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Postdoctoral Fellow and Graduate Research
Assistant Positions Available
Featured News Check out our most recent work published in Nature Immunology! Guo Y, High-throughput and high-dimensional single-cell analysis of antigen-specific CD8+ T cells from JRNLclub on Vimeo. Nov 15, 2024 Dr. Jiang gave an invited talk at the 6th Annual Immune Modulation and Engineering Symposium at Drexel University Nov 8, 2024 Dr. Jiang was invited to give a presentation at the Penn Center for Precision Engineering in Medicine Symposium - Engineering's Role in Precision Medicine, invited by Dr. Dan Hammer at University of Pennsylvania, Philadelphia Oct 30, 2024 Dr. Jiang along with Dr. Ivan Marazzi at University of California, Irvine, Dr. Soyon Hong at University College London, Dr. Chris Bennett at UPenn, and Dr. Margaret Sutherland at CZI Symposium Immune System in Neurodegeneration. Sep 23, 2024 Congratulations to Dr. Jiang for receiving the 2025 CMBE Momentum Award! Jul 10, 2024 Dr. Jiang was invited to give a presentation at the Chan Zuckerberg Initiative Neuroscience 2024 Annual Meeting in Monterey, California. Jun 25, 2024 Dr. Jiang was invited to give a presentation at the 15th International Conference on Genomics and Systems Biology of Human Disease and Aging May 7, 2024 Congratulations to Xiangcheng (Ison) Chen for receiving a Trainee Abstract Awards! May 6, 2024 Congratulations to Yuwan Guo for giving a podium presentation at the American Association of Immunologists Annual Meeting and also received a Trainee Abstract Awards! Feb 29, 2024 Dr. Jiang was invited to give a presentation at the Department of Biomedical Engineering, Washington University in St Louis. Feb 8, 2024 Dr. Jiang was invited to give a presentation at the CZI Ben Barres Early Career Acceleration Award awardee symposium. Jan 16, 2024 Dr. Jiang gave an invited talk at the 2024 Johns Hopkins Center for Translational ImmunoEngineering Workshop. Jan 3-6, 2024 Dr. Jiang and Dr. Ben Cosgrove at Cornell successfully organized the 2024 CMBE conference held in Puerto Rico. The theme of the conference is "Systems Bioengineering: From Molecules to Cells to Tissues." Jan 3, 2024 Congratulations to Dr. Jiang for being elected as the council Chair of the Cellular and Molecular Bioengineering Significant Interest Group of Biomedical Engineering Society! Oct 26, 2023 Dr. Jiang was invited to give a presentation at the 3rd Human & Translational Immunology Conference, Rhodes, Greece. Oct 25, 2023 Congratulations to Shahab (Shawn) Chizari for receiving a CMBE 2024 Graduate Student Travel Award! Oct 9, 2023 Dr. Jiang gave an invited talk at the Ecole polytechnique federale de Lausanne (EPFL) Bioengineering seminar. Sep 14, 2023 Dr. Jiang was invited to give a presentation at Physical Biology of the Cell 2023. Sep 7, 2023 Congratulations to Shahab (Shawn) Chizari for receiving the T32 training award! Aug 21, 2023 Connor Devin, a new first year Bioengineering Ph.D. student, joins the lab. Welcome Connor! Aug 8, 2023 Dr. Jiang gave an invited talk at the Chan Zuckerberg Initiative Inaugural Neurodegenerative Diseases Computational Fellow Bootcamp. Jul 14, 2023 Dr. Jiang was invited to give a presentation at the Institute of Immunology, Shanghai Jiaotong University, invited by Dr. Feng Wang. Jun 30, 2023 Dr. Jiang was invited to give a presentation at Zhejiang University, Liangzhu Laboratory, invited by Dr. Jack Wei Chen. Jun 9, 2023 Dr. Jiang was invited to give a presentation at the Chan Zuckerberg Initiative Neurodegeneration Challenge Network annual meeting. Jun 7, 2023 Dr. Jiang gave an invited talk at the University of Pennsylvania Institute for Immunology and Immune Health Year in Review Symposium. Jun 7, 2023 Dr. Jiang gave an invited talk at the Keystone Symposia on B Cell Biology in the Context of Infectious Diseases, Autoimmunity and B Cell Cancers. May 13, 2023 Congratulations to Michael Malone, Jack Prazich, and Shahab (Shawn) Chizari for giving podium presentations at the American Association of Immunologists Annual Meeting and also receiving the Trainee Abstract Awards! Apr 27, 2023 Dr. Jiang was invited to give a presentation at the UNC TCR Think Tank Conference. Apr 20, 2023 Dr. Jiang was invited to give a presentation at the Cold Spring Harbor Meeting - Systems Immunology, invited by Dr. Harinder Singh at the University of Pittsburgh. Feb 8, 2023 Dr. Jiang was invited to give a presentation at the FASEB Catalyst Conference - Immune Repertoire Decoding. Jan 25, 2023 Dr. Jiang was invited to give a presentation at the NCI Emerging Technologies Seminar Series. Jan 19, 2023 Dr. Jiang gave an invited talk at the Department of Biomedical Engineering, Penn State, invited by Dr. Spence Szczesny (online presentation). Nov 10, 2022 Dr. Jiang gave an invited talk at the Department of Immunology, University of Pittsburgh, invited by Dr. Mark Shlomchik. Oct 20, 2022 Dr. Jiang gave an invited talk at the 4th Systems Approaches to Cancer Biology conference at the Marine Biological Laboratory (MBL) in Woods Hole, MA. Aug 22, 2022 Steven Kong, a new first year Bioengineering Ph.D. student, joins the lab. Welcome Steven! Jul 28, 2022 Dr. Jiang was invited to give a presentation at the iReceptor Plus Seminar Series. Jul 27, 2022 Dr. Jiang was invited to give a talk at the Penn Wharton China Center - Engineering virtual tech talk series. Jul 13, 2022 Dr. Jiang gave an invited talk at the 2022 Gordon Research Conference on Immunoengineering, Ventura, CA. Jun 22-27, 2022 Dr. Jiang was invited to present TetTCR-SeqHD technology at the 14th International Conference on Genomes, Pathways, and Systems Medicine organized by Drs. Bing Ren at UCSD, Shankar Subramaniam at UCSD, and Ana Pombo at Humboldt University on the island of Rhodes in Greece. May 16, 2022 Dr. Jiang was invited by Dr. Jarrod A. Dudakov to give a seminar at Fred Hutchinson Cancer Research Center. May 10, 2022 Dr. Jiang was invited by Dr. Warren Chan to give a seminar at the Institute of Biomaterials & Biomedical Engineering (IBBME) at the University of Toronto Invited Speaker Seminars series. May 7, 2022 Congratulations to Yuwan Guo and Jack Prazich for giving two fantastic talks at AAI 2022! Apr 21, 2022 Dr. Jiang was invited by Dr. Chris Vollmers to give a seminar at the Department of Biomolecular Engineering, UC Santa Cruz. Apr 12, 2022 The Breakout Panel: Technologies for Health Innovation and Accessibility that Dr. Jiang organized at the National Academy of Medicine 2022 Emerging Leaders in Health and Medicine Forum was a big success! Feb 2, 2022 A fantastic JRNLclub recording of our TetTCR-SeqHD paper presented by our current lab member, Yuwan Guo! Nov 22, 2021 Kevin and Alex's TetTCR-SeqHD paper was published in Nature Immunology today. Congratulations! Jan 5, 2022 Congratulations to Michael Malone for giving a podium presentation at the CMBE Annual Meeting! Oct 7, 2021 Congratulations to Michael Malone for giving a podium presentation at the BMES Annual Meeting! Sep 8, 2021 Dr. Jiang presented at the BD Insights Immunology 2021 virtual symposium Aug 25, 2021 Ison Chen, a first year Penn Bioengineering student, just joined the lab. Welcome Ison! July 19, 2021 Congratulations to Dr. Jiang for receiving a 2021 Lloyd J. Old STAR award from the Cancer Research Institute! Jun 1, 2021 The Jiang Lab has moved from the University of Texas at Austin to the University of Pennsylvania! For all news, please click here |
